Healing From Grief & Loss | Dr. Mary-Frances O'Connor

Healing From Grief & Loss | Dr. Mary-Frances O'Connor

Huberman Lab · 2025-06-02

My guest is Dr. Mary-Frances O’Connor, PhD, Professor of Clinical Psychology and Psychiatry at the University of Arizona and a world expert on the science of grief and loss. We discuss what happens in the brain and body when we grieve, the role of dopamine and yearning in the grieving process, the health risks of getting stuck at particular stages of grief and how to move through loss while also deeply honoring the person, animal or thing that is no longer with us. Dr. O’Connor explains that grief involves cycling back and forth between protest and despair (often guilt and anger too) and explains science-supported ways to move through that process in the healthiest possible way. Everyone experiences grief and loss at some point. Dr. O’Connor provides valuable knowledge and tools to help you navigate grief under any circumstance.Read the episode show notes at hubermanlab.com.Thank you to our sponsorsAG1: https://drinkag1.com/hubermanWealthfront**: https://wealthfront.com/hubermanBetterHelp: https://betterhelp.com/hubermanHelix Sleep: https://helixsleep.com/hubermanFunction: https://functionhealth.com/huberman**This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer.Timestamps00:00:00 Mary-Frances O’Connor00:02:22 Grief vs Grieving; Love & Bonding, Gone Yet Everlasting00:07:42 Sponsors: Wealthfront & BetterHelp00:10:29 Sudden vs Slow Death, Attachment, Reframing Relationship00:14:52 Religion, Integrating the New Relationship00:20:46 Yearning, Dopamine, Brain, Addiction00:27:58 Culture & Grief Literacy; Protest, Despair & Hope, New Relationships00:40:09 Sponsors: AG1 & Helix Sleep00:43:21 Protest, Despair & Transmutation; Changing Attachment Hierarchy00:52:04 Bereavement Support, Medical Risk01:05:27 Culture, Alcohol & Death; Dying of a Broken Heart, Medical Risk01:13:40 Sponsor: Function01:15:28 Navigating Grief, Emotions & Body, Tool: Progressive Muscle Relaxation01:23:57 Grief Stages; Permission & Coping, Judgment & Guilt; Lessons from Grief01:35:44 Grieving Suicide, Rumination, Tool: Shifting Environment 01:47:24 Belief Systems, Religion & Grief01:54:17 Afterlife, Contemplating Death 01:58:35 Tools: Contemplating Death; Life Celebration, Terror Management, Empathy02:07:46 Mental Oscillation, Dual Model of Bereavement 02:14:00 Avoidance; Remembering a Loved One, Resilience; Getting Worse & Seeking Professional Help02:22:15 Time Perception & End of Life, Motivation & Energy02:30:01 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & DisclosuresLearn more about your ad choices. Visit megaphone.fm/adchoices

Huberman Lab

The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.
Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017.
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.

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